Divigel® is the Clear Choice


Relief from moderate to severe vasomotor symptoms (hot flashes and night sweats) due to menopause

Gel droplet.

Proven Relief

Divigel® eliminated nearly 90% of hot flashes in 12 weeks and reduced hot flashes by nearly HALF in as little as 2 weeks (1 mg/day).1

Discrete Divigel® gel package.

Discreet Gel Pack

Divigel® is a cool, clear estradiol gel that’s easy to apply. It comes in small packets that are convenient for travel. Divigel® is applied once a day to a small area of the upper thigh. Divigel® is invisible and odorless when dry, and leaves no sticky residue.

To reduce the risk of transmission, advise patients to wash hands, avoid skin contact until gel is completely dried, and cover the application site.

Divigel® comes in 0.25 mg, 0.5 mg, 0.75 mg, 1 mg, and 1.25 mg.

The Divigel® Product Lineup

Available in five strengths including the lowest FDA-Approved dose of transdermal estradiol gel or spray: 0.25 mg, 0.5 mg, 0.75 mg, 1 mg and 1.25 mg estradiol to provide tailored relief of vasomotor symptoms to your patients.2

Image of a Divigel® savings coupon.

Unlock Patient Savings

Divigel® is one of the lowest cost transdermal estrogen gels.3 Save more money for your patients with the Divigel® Patient Savings Coupon.

Discreet gel packet carrying case.

Get Divigel® Samples

If you are a physician or other healthcare professional in the U.S., you can receive Divigel® samples by mail to support patient trial and use. Divigel® samples come with a convenient travel case for your patients.

If your practice is in a location where we have a sales representative, one will visit your office to provide you with Divigel® information and samples.

Order Samples

1. Hedrick RE, Ackerman RT, Koltun WD, Halvorsen MB, Lambrecht LJ. Transdermal estradiol gel 0.1% for the treatment of vasomotor symptoms in postmenopausal women. Menopause. 2009;16(1):132-140.
2. Orange Book: Approved Drug Products with Therapeutic equivalence Evaluations. U.S. Food & Drug Administration. Accessed February 13, 2020. https://www.accessdata.fda.gov/scripts/cder/ob/search_product.cfm
3. Data on file, Osmotica Pharmaceuticals, November 2019.

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