Stay Cool with Divigel® The #1 prescribed gel with plant-based estrogen1.

Divigel® is FDA-approved to treat moderate to severe vasomotor symptoms (hot flashes and night sweats) due to menopause.

Proven Relief From Hot Flashes and Night Sweats*

  • Eliminated nearly 90% of hot flashes in 12 weeks at the highest dose strength (1 mg/day).2
  • Reduced hot flashes by nearly HALF in as little as 2 weeks (1 mg/day).2
  • Comes in three dose strengths, including the lowest FDA approved dose.
  • At the lowest dose (0.25 mg/day) Divigel® eliminated about 70% of hot flashes in 12 weeks.2
  • On Divigel® you will not only experience fewer hot flashes and night sweats over time, but they will also be less severe.2,3

*The FDA recommends the lowest effective dose with any estrogen therapy.4 Only Divigel® offers the lowest FDA-approved dose of transdermal estradiol gel or spray available for hot flashes (0.25 mg/day estradiol).3,5-7

Plant-Based and Bioidentical

  • Estradiol, the active ingredient in Divigel®, comes from plants.
  • It is chemically identical to the estrogen naturally produced by your body before menopause.

Cool, Discreet Gel

  • Divigel® is a fast drying, cosmetically elegant gel that leaves no sticky residue.
  • It’s invisible and odorless when dry. Nobody knows you’re wearing it.
  • It’s a concentrated estradiol gel, so only a small amount is needed for big relief.

Easy to Use and Convenient

  • A small amount of Divigel® is applied once daily to the upper thigh.
  • The gel comes in small, portable packets that are easy to use at home and great for travel.
  • Premeasured, daily packets ensure precise, accurate dosing.
  • Divigel® becomes part of your daily personal care routine.


Divigel® delivers estrogen directly through the skin to the bloodstream, avoiding the stomach and liver. This way, therapies applied to the skin, such as Divigel®, can be used at lower doses to achieve similar relief as hormone pills.8, 9


Easy to Apply
Once Daily
Cool Relief



Ask your doctor for a free sample of Divigel® to help you get started. Each sample comes with 7 days of therapy and a travel case. Your doctor can order samples here.


We offer a copay savings program. Divigel® is covered by most commercial insurance companies. Bring your prescription to the pharmacy along with your coupon.


Learn how to apply Divigel®, what to know before you start and find answers to common questions.

1. IMS Data, 2017. 2. Hedrick RE, Ackerman RT, Koltun WD, Halvorsen MB, Lambrecht LJ. Transdermal estradiol gel 0.1% for the treatment of vasomotor symptoms in postmenopausal women. Menopause. 2009;16(1):132-140. 3. Divigel ® [package insert]. Vertical Pharmaceuticals, LLC; 2017. 4. US Food and Drug Administration. Menopause and hormones. Updated June 14, 2017. Accessed July 18, 2017. 5. EstroGel® [package insert]. Herndon, VA: ASCEND Therapeutics, Inc.; 2014. 6. Elestrin® [package insert]. Somerset, NJ: Meda Pharmaceuticals; 2014. 7. Evamist® [package insert]. Minneapolis, MN: Perrigo; 2015. 8. Goodman NF, Cobin RH, Ginzburg SB, Katz IA, Woode DE; American Association of Clinical Endocrinologists. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the diagnosis and treatment of menopause. Endocr Pract. 2011;17(suppl 6):1-25. 9. Samsioe G. Transdermal hormone therapy: gels and patches. Climacteric. 2004;7(4):347-356.

400 Crossing Blvd.
Bridgewater, NJ 08807

Phone: 908-809-1300

Contact Us